Cat Lake First Nation (Ojibwe: Bizhiw-zaaga'igan, ᐱᔕᐤ ᓴᑲᐦᐃᑲᐣ)[4] is an Ojibway First Nation reserve approximately 180 kilometres northwest of Sioux Lookout in northwestern Ontario, Canada, located on the central north shore of Cat Lake.

Cat Lake First Nation is currently in a state of emergency due to the presence of dangerous levels of black mould in the homes.

On March 14, 2019, an agreement worth $12.8 million was agreed to with the federal government to address the crisis.

The community of Cat Lake was originally established as a Hudson's Bay Company trading post in 1788, and later belonged to the Osnaburgh Band of Ojibwe.

North Star Air and Slate Falls Airways run daily service on regular schedules to Cat Lake Airport.