Caterina Scarpellini (29 October 1808 – 28 November 1873) was an Italian astronomer who discovered a comet and as a meteorologist she established a station in Rome in the 1850s.

She was born in Foligno on 29 October 1808, Scarpellini moved to Rome at the age of 18.

[1] Scarpellini was not allowed to become a member of the Accademia dei Lincei, which her uncle had helped re-establish in 1801.

Along with her husband, Erasmo Fabri, she established a meteorological station in Rome in 1856.

[3] In 1872 she was honored by the Italian government for her work; she died 28 November the following year.