The Holy Cathedral Church of the Annunciation of the Theotokos (Greek: Ιερός Καθεδρικός Ναός Ευαγγελισμού της Θεοτόκου Αλεξάνδρειας, romanized: Ieros Kathedrikos Naos Evangelismou tis Theotokou Alexandrias) is a trilateral basilica which was founded in the middle of the 19th century in Alexandria, Egypt.

Completion of the work took nine years, which was officially marked on 25 March 1856 with a liturgy celebrated by Patriarch Hierotheus.

Restoration work was completed in December 2004 with funding from the Alexander S. Onassis Foundation.

The marble iconostasis, patriarchal throne, the sedilia and the ambo were all works by the Constantinopolitan Iakovos Varoutis.

For the design of the doors, windows, pews, baldachin and other sculpture the work was done by George Philippides.