The cathedral is historically known for its music ministry, led by Canon Lawrence Tremsky (Northwestern University, M.M.).

The choirs sing a repertoire of choral music, from plainsong to modern works, selected carefully to coincide with the themes of the season.

Evensong is sung on the first Sunday of each month in the traditional English cathedral model (Magnificat, Nunc Dimittis, an anthem, and Anglican chant psalms).

Special seasonal liturgies include traditional "Lessons & Carols" one or two Sundays before Christmas.The cathedral is notable for its stained glass windows and icons.

The mural icon of Christ Pantokrator, permanently installed at the cathedral, was crafted by the American artist Guillermo Esparza.