The Cathedral of the Nativity of Christ (Coptic: ⲡⲓⲉⲣⲫⲉⲓ ⲛ̀ⲕⲁⲑⲉⲇⲣⲁ ⲛ̀ⲧⲉ ⲡϫⲓⲛⲙⲓⲥⲓ ⲙ̀ⲡⲭⲣⲓⲥⲧⲟⲥ, romanized: Pi-erfey EnKathedhra Ente Epjinmisi EmPi-Ekhrestos, lit.

[3][6] In January 2017, following twin terrorist attacks that killed at least 27 Coptic Egyptians at St. Peter and St. Paul's Church in Cairo in December 2016, the President of Egypt Abdel Fattah el-Sisi commissioned the construction of the country's largest mosque and church in the new administrative capital to become symbols of coexistence and national unity.

[8] On the same day of the inauguration, Divine Liturgy was celebrated in the chapel of the cathedral with the participation of some 3,000 people that included representatives from all over the country.

Imam Sheikh Ahmed El-Tayeb called it "the embodiment of the soul of brotherhood and love".

[6] It contains a main square and papal headquarters, a reception hall, a meeting room and administrative offices.