[1] Freudenreich spent her childhood in Los Alamos, New Mexico, before attending Rice University, where she graduated in 1988 with a B.A in biology.
[3] Freudenreich then undertook further postdoctoral research at Princeton University with Virginia Zakian, studying CTG repeats in yeast.
[1] Freudenreich’s lab studies genome instability in yeast, with the aim of uncovering mechanisms of genetic disease and cancer.
In particular, much of her research has focused on conserved trinucleotide repeat sequences, specifically CAG/CTG, and their contributions to genome fragility and instability.
[5][6][7] Recently, Freudenreich’s group looked at CAG/CTG repeats in Huntington’s disease, finding that the cells’ attempts to repair CAG sequences often lead to large, deleterious deletions.