She is best known for her work with Jesse Malin, Ryan Adams & the Cardinals, Grace Potter and the Nocturnals and Jack White.

On November 14, 2011, Popper announced her departure from Grace Potter and the Nocturnals for the "foreseeable future" on her Facebook page.

In January 2012, Popper appeared on Late Show with David Letterman, performing "Travel As Equals" with Joseph Arthur.

In 2013, Popper appeared on four tracks on Joseph Arthur's tenth studio album, The Ballad of Boogie Christ.

with Hem with Ryan Adams and the Cardinals with Willie Nelson with Rachael Yamagata with Grace Potter and the Nocturnals with Joseph Arthur with Mike Doughty with Jack White with Puss n Boots with Levon Helm with Jesse Malin with Brian Fallon with D Generation with Bash And Pop with She And Him with Manolo Garcia Broadway Cast Recordings Film and Television