Catherine of Saxony (German: Katharina von Sachsen; 24 July 1468 – 10 February 1524),[1] a member of the House of Wettin, was the second wife of Sigismund, Archduke of Austria and Regent of Tyrol.

Born in Grimma, Catherine was the eldest child of Duke Albert III of Saxony and his wife, the Bohemian princess Sidonie of Poděbrady.

Her paternal grandparents were Elector Frederick III of Saxony and Margaret of Austria, daughter of the Habsburg duke Ernest the Iron.

As the political style of the archduke was no longer tenable, he was gradually losing control over his Tyrolean possessions to his cousin Emperor Frederick III.

Soon after the archduke's death on 4 March 1496, Catherine married the Welf duke Eric I of Brunswick-Lüneburg, ruler over the Principality of Calenberg.