Neighbouring municipalities of Cavarzere are: Adria, Agna, Anguillara Veneta, Chioggia, Cona, Loreo, Pettorazza Grimani, San Martino di Venezze.

Cavarzere dates from the pre-Roman age as a military outpost of the nearby town of Hatria, the future Adria.

For this viable location (along the River Adige and not far from the Venetian Lagoon) as the last town before the Papal States, Cavarzere was destroyed by many artificial floods and invasions by the Lombards, the Genoese, the French and also from the Duchy of Ferrara.

Cavarzere is served by a bus service providing regular transport to all parts of the area and neighbouring towns, based on a large station.

Cavarzere is home to a small hospital belonging to ULSS 14 of Chioggia, a medical outpost named "cittadella socio-sanitaria".