It then traverses the municipalities Consolacion, Liloan (where it begins to follow along the western coast of Cebu), and Compostela and the city of Danao.

The road then passes through the towns of Carmen, Catmon, Sogod (where it veers away from the western coast to cut through the mountains of Cebu), Borbon, and Tabogon before entering the city Bogo.

At a junction with the Antonio y De Pio Highway (N820) in San Remigio proper, the roads turns north, initially following the northeastern coast of Cebu.

The entire road historically forms part of Cebu Island's Highway 1 or Route 1 during the 20th century.

[5][6] The road's eastern section in Cebu City was historically known as Calle Enrile (in honor of Governor-General Pasqual Enrile y Alcedo) and later Calle de los Martires (for being the site where Katipuneros and civilians were ordered killed after the Battle of Tres de Abril in 1898).