Cell CANARY

[2] In 2007, Benjamin Shapiro, Pamela Abshire, Elisabeth Smela, and Denis Wirtz were granted a patent entitled “Cell Canaries for Biochemical Pathogen Detection.

They have successfully manipulated the sensors so that they are sensitive to exposure of certain dangers, such as explosive materials or biological pathogens.

[5] It has the ability to detect pathogens in a variety of media, both liquid and air, at a fraction of the concentration that older methods required to produce a viable signal.

[8] The emitted photons can then be read by a chip, on which the array of modified B cells have been attached to, ultimately providing a readout of the pathogen(s) present.

A patient would be able to visit a medical professional, provide a sample of blood or urine, and get an analysis within minutes.

High profile and even regular office buildings could have these sensors in every corridor to proactively hunt out air-borne pathogens, leaving enough time for evacuation.

Full-length
Step1: B cells are exposed around by antigens. Step2: antigens are attached with antibodies. Step3: tyrosine kinase leads to IP3 and DAG, Ca2+ is released. Step4: Ca2+ channel is opened and aequorin emits photons. Step 5, photons are detected.