Cell adhesion molecule 1

3BIN, 4H5S2370554725ENSG00000182985ENSMUSG00000032076Q9BY67Q8R5M8NM_001098517NM_001301043NM_001301044NM_001301045NM_014333NM_001025600NM_018770NM_207675NM_207676NM_001310841NP_001091987NP_001287972NP_001287973NP_001287974NP_055148NP_001020771NP_001297770NP_061240NP_997558NP_997559Cell adhesion molecule 1 is a protein that, in humans, is encoded by the CADM1 gene.

[5][6] Cell adhesion molecule 1 has been shown to interact with EPB41L3.

[8] Experimental results of another study showed that obese mice had an over expression of both CADM1 and CADM2 genes, and that loss of CADM1 protected mice from obesity, promoting a negative energy balance and weight loss.

[9] Furthermore, a 2019 GWAS study revealed an association between Anorexia nervosa and CADM1.

[10] In the brain, this genes mediate synaptic assembly, and mutations in CADM1 are also associated with Autistic spectrum disorder.