His only signed work is the fresco of the True Cross at the Cappella della Croce di Giorno at the church of San Francesco in Volterra, painted in 1410.

[1] A couple of dozen works have been attributed to Cenni di Francesco on the basis of a similarity of style with the fresco.

[2] A Polyptych with Coronation of the Virgin and Saints (circa 1390) is on display in the Getty Museum in California.

A fresco depicting the Madonna Enthroned with Angels and the Cardinal and Theological Virtues in the town hall of San Miniato al Tedesco dates back to 1393, while the frescoes in San Donato in Polverosa in Florence seem to date back to 1383.

Around these certain and certainly dated works can be grouped others, referred to him by recent critics , that integrate the brief catalogue by Cavalcaselle (1897) already recognised to the painter, making him considered to be one of the most pleasant and lively interpreters of Florentine taste between the 14th and 15th centuries.