The Act came into effect on 26 January 1993 with the issue of necessary notification by the Department of Agricultural Research and Education (DARE), Government of India.

The jurisdiction of the university extends to seven North-Eastern Hill States: Arunachal Pradesh, Manipur, Meghalaya, Mizoram, Sikkim, Nagaland and Tripura.

), research and extension activities at College of Veterinary Sciences & Animal Husbandry, Selesih, Aizawl, Mizoram.

As per the mandate, the university has established 13 different constituent colleges, 6 KVKs, 6 Multi Technology Testing Centers: In six states at Manipur, Mizoram, Tripura, Arunachal Pradesh, Sikkim and Meghalaya 6 Vocational Training Centers: In six states at Manipur, Mizoram, Tripura, Arunachal Pradesh, Sikkim and Meghalaya.

There are Thirteen colleges under CAU: The Central Agricultural University, Imphal located at Lamphelpat, Imphal West, Manipur has its area of jurisdiction over seven North-Eastern Hill (NEH) states of India except Assam.