The Coloso origins begin in the 19th century, specifically towards the end of the 1820s when the Caño de las Nasas estate was founded in Aguada.

Still, due to high debts and the crisis in the sugarcane industry in the late 19th century, Kuster & Vadí sold Coloso to José Arnell Massó in 1897.

After buying Central Coloso, Arnell Massó consolidated it with other refinery and sugar mills he had acquired between 1885 and 1895.

As a result of this, Central Coloso ended up covering 4,370 acres, of which approximately 500 were cultivated annually.

The sugar industry started struggling towards the middle of the 20th century due to several reasons: high cost of production, declining sale prices, credit restrictions, and strikes among workers.

During the 1980s, most of the sugar mills and refineries in the island had ceased operations, but Coloso maintained a considerable production tonnage.

The Coloso Bridge, used for the transport of sugarcane across the Culebrinas River, was added to the National Register of Historic Places on December 29, 2010.

[1] In 2016, twenty-one families were given property title deeds to Central Coloso land, where they had lived for more than five decades.