The Central Commission for the Navigation of the Rhine (CCNR; French: Commission centrale pour la navigation du Rhin; German: Zentralkommission für die Rheinschifffahrt; Dutch: Centrale Commissie voor de Rijnvaart) is an international organisation with five member countries, whose function is to encourage European prosperity by guaranteeing a high level of security for navigation of the Rhine and environs.

The United States was temporarily a member immediately after the World War II, while Germany was under Allied occupation, until 1961.

[7] Since 1920, the headquarters of the commission has been located in Strasbourg, in the former imperial palace, renamed the Palais du Rhin, which also houses the Regional Directorate of Cultural Affairs of Alsace.

[10] Legally, the commission's authority comes from agreements made at the Congress of Vienna, held in 1815 in the aftermath of the Napoleonic Wars.

[12] Following the Franco-Prussian War of 1870, the commission primarily played the role of a German-Dutch bilateral body, France having ceased to be a member after the Treaty of Frankfurt (1871).

[12] After the end of the First World War, the commission's headquarters was moved to Strasbourg in 1920 as part of the Treaty of Versailles.