The Central Institutional Organization Commission, sometimes synonymous with the State Commission for Public Sector Reform, is an agency of the Central Committee of the Chinese Communist Party with full jurisdiction also over the State Council of China as well as lower and local government bodies.

It is led by the Premier of the State Council and closely tied to the Organization Department of the Chinese Communist Party.

During its history, the Commission changed name several times between the establishment of the People's Republic of China and the adoption of its current name and functions in 1991.

The commission oversees institutional reforms and staffing structures of the CCP Center and the State Council.

There is also the State Commission Office for Public Sector Reform, which serves as its executive organ.