When completed in 2025, it will form the section of the planned Route 6 which runs through the Kowloon Peninsula, largely underground.

From there, Route 6 is planned to continue to Tseung Kwan O, although the section beyond Kai Tak is not part of the CKR project.

The proposed alignment will lead to the demolition of numerous structures including the Yau Ma Tei Car Park Building, a public library, the jade hawker bazaar, and the Yau Ma Tei Specialist Clinic Extension.

In January 2016, the Hong Kong Executive Council approved construction of the Central Kowloon Route.

An excavator being lifted by a tower crane broke loose and plunged down a giant ventilation shaft in Ho Man Tin.