The Central PA Vipers were a team of the Independent Women's Football League.

Based in the Steelton suburb of Harrisburg, Pennsylvania, the Vipers played their home games at Steelton-Highspire School District's War Veterans Memorial Field, also known as Cottage Hill.

Prior to playing in the IWFL, the Vipers were a member of the National Women's Football Association in 2006 and 2007 (in their inaugural season, they were called the Harrisburg Angels).

After four seasons and twenty-seven attempts (not counting two forfeits by the Richmond Spirit in 2007), the Vipers finally picked up their first victory on the gridiron on June 6, 2009 thanks to a 48-0 triumph over the Holyoke Hurricanes.

The following week, the Vipers continued their string of success, defeating the Cape Fear Thunder, 30-6.