The Central Region (Maltese: Reġjun Ċentrali) is a former region of Malta.

The region included the central part of the main island of Malta, and bordered the Northern, Southern and South Eastern Regions.

XVI of 2009 out of part of Malta Majjistral.

XIV of 2019 replaced the region with Eastern Region, significantly changing its composition[2] Central Region included parts of the Northern Harbour and Western Districts.

Central Region included 13 local councils: The last Central Regional Committee (Maltese: Kumitat Reġjonali Ċentrali) was made up of:[3]