It is an extensive plain located in the transition zone between Central and Eastern Siberia and is one of the Great Russian Regions.

The main city is Yakutsk, with a number of settlements near it, but the area of the lowland is largely uninhabited elsewhere.

Owing to poor drainage, swamps and thermokarst lakes (alases), are common,[8] as well as low bulges or bumps known as "bulgunnyakh" (Yakut: Булгунньах).

[9] In the northwest the Tukulan (Тукуланы) sand dunes are relief forms shaped by aeolian processes along the valley of the Lena River.

The entire length of the course of some of the large left tributaries of the Lena, such as the Lungkha, Tyugyuene, Sitte, Khanchaly and Kenkeme, falls wholly within the lowland area.