It is also known as Pichincha giant glass frog or bumpy glassfrog.

[3] In Ecuador it has been recorded from the western Andes in the Pichincha and Santo Domingo de los Tsáchilas Provinces.

[4] Centrolene heloderma are small frogs (although among the generally small Centrolene, they are relatively large[5]): males measure 27–32 mm (1.1–1.3 in) in snout–vent length and females 32 mm (1.3 in) (based on one frog only).

[4][6] Females lay clutches up to 29 eggs on the upper side of leaves and very high from the water level.

[1] Its disappearance has been attributed to changing climatic patterns, with habitat loss, alien predatory fish, pollution, and chytridiomycosis as other potential contributing factors.