The journal was established in 1981 and currently has 16 issues per year.

[1] The journal is abstracted and indexed in MEDLINE,[2] Scopus,[3] the Science Citation Index,[4] Current Contents/Clinical Medicine,[4] Current Contents/Life Sciences,[4] and BIOSIS Previews.

[4] According to the Journal Citation Reports, its 2020 impact factor is 6.292.

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