"[8] Murray won a scholarship to attend a modeling convention in Orlando, Florida, where he met an agent who encouraged him to go to Los Angeles for a week and see what happens.

[9] In 2000, he guest starred as Dan on the MTV drama anthology series Undressed on the episode "Scared Stiffy" which aired on March 8 as part of its second season.

He ended his debut year on screen appearing on the November 16 episode of the CBS crime drama Diagnosis: Murder during its eighth season.

[10][11] Murray portrayed the role of teenage David Alexander in Christian Apocalyptic fiction film Megiddo: The Omega Code 2 which released on September 7.

Murray was cast in the role of womanizer Charlie Todd on The WB's hit television series Dawson's Creek as a recurring character in the fifth season which premiered on October 10.

He next played the lead role of Luke Hartman on The WB's western television film The Lone Ranger which aired on February 26 and served as a backdoor pilot for a potential series run.

Murray was cast in the role of love-interest Jake in the Walt Disney Pictures comedy film Freaky Friday, starring Lindsay Lohan and Jamie Lee Curtis, which released in theaters on August 6.

The series was one of The WB's most successful programs the year it began and continued with impressive ratings after the network merged with rival UPN to become The CW in 2006.

Stemming from the series' popularity, he and his One Tree Hill co-stars became official endorsers for MasterCard, K-Mart,[13] Cingular Wireless and the Chevy Cobalt.

[14] In 2004, Murray starred as Austin Ames in the romantic comedy film A Cinderella Story alongside Hilary Duff which released in July 16.

[26] Murray played the role of Ethan McAllister in the drama television film Lies in Plain Sight which aired on Lifetime on October 3, 2010.

He played the love-interest Patrick Kerns in the television film Christmas Cupid, alongside Christina Milan and Ashley Benson, which premiered on ABC Family on December 12.

[27][28] On August 29, 2011, The CW announced that Murray would return for a guest appearance as Lucas Scott in the final season of One Tree Hill.

The film is based on the true story of Tworkowski's founding of the Florida-based non-profit organization of the same name helping those struggling with addiction, mental illness and self-injury, and received a limited theatrical release on March 3, 2015.

[30] Murray next starred as Dylan in the Funny or Die short First Kiss alongside Rachael Leigh Cook which released on September 11.

Murray next played male lead Andy Wyrick in the horror film The Haunting in Connecticut 2: Ghosts of Georgia which released on February 1.

[33][34] He guest starred as Officer Dave Mendoza in the crime drama series Southland on two episodes during its concluding fifth season which premiered on TNT on February 13.

Murray next co-starred in the apocalyptic thriller film Left Behind, playing the role of Cameron "Buck" Williams, alongside Nicolas Cage and Jordin Sparks.

[39] Later in 2015, he guest starred on the Fox black comedy series Scream Queens on a November 24 episode during its first season, playing Chad Radwell's older brother Brad.

On March 14, 2016, it was reported that Murray was cast to star as Sam Phillips in the CMT biographical drama series Million Dollar Quartet.

[44] In 2018, he played the male lead Brett Beauchamps in the drama television film The Beach House, alongside Minka Kelly and Andie MacDowell, which premiered on the Hallmark Channel on April 28.

On August 27, 2018, it was reported that Murray was cast in a recurring role as Xander McPherson, the toxic love-interest of Cassie Brown as played by Brandy Norwood, in the third season of the musical drama Star which premiered on Fox on September 26.

[48] He next starred as Paul Barnett in the film Too Close for Christmas which received a limited theatrical release on November 13,[49] before premiering on Lifetime on December 4.

In 2021, he starred as Joel Sheehan in the film Colors of Love which received a limited theatrical release on February 4,[51] before premiering on GAC Family on October 23 under the title An Autumn Romance as its first original movie.

[70] On April 6, 2006, it was reported that Murray was engaged to Kenzie Dalton, an actress and Miss North Carolina Teen USA 2006 runner-up; at the time, he was 24 and she was 18.