Chanel (Emma Roberts) finds a new project in Hester (Lea Michele), and Dean Munsch (Jamie Lee Curtis) appoints a new Wallace University mascot while trying to separate Gigi (Nasim Pedrad) and Wes (Oliver Hudson)'s budding relationship as Chad (Glen Powell) and Earl Grey (Lucien Laviscount) lead their fraternity on a witch hunt for the Red Devil.

Due to Chanel #2's mysterious absence, Zayday and Grace visit her parents in Bel Air, California to find out what happened.

Chad and Earl Grey encourage The Dickie Dollar Scholars fraternity to organize a witch hunt, to avenge Boone's "death".

Niecy Nash returns as special guest star portraying Denise Hemphill, the odd security guard.

Returning recurring characters in this episode include Kappa pledges Jennifer "Candle Vlogger" (Breezy Eslin), Sam "Predatory Lez" (Jeanna Han), and Dickie Dollar Scholars fraternity members Caulfield (Evan Paley), and twins Roger and Dodger (Aaron and Austin Rhodes).

Before the series started, back on June 24, 2015, it was announced that Charisma Carpenter and Roger Bart had been cast in a guest role as Chanel #2 (Ariana Grande)'s parents.

"[6] Caralynn Lippo, from TV Fanatic, gave the episode 4 out of 5 stars, citing that Chainsaw "somehow managed to up the campy quotient that was already prevalent in the series premiere.