Challney High School for Girls is a comprehensive secondary school for girls, located in the Challney area of Luton, Bedfordshire, England.

For further education courses such as A levels, graduating students usually go on to attend Luton Sixth Form College.

In 2006, Challney High School for Girls was awarded specialist status as a Science College.

The academy still operates under the name Challney High School for Girls, within the Chiltern Learning Trust.

This Bedfordshire school or sixth form college related article is a stub.