He has an older brother, Colby, who is also an actor, and a younger sister named Shelby, an actress.

[1] Canterbury starred in the thriller Knowing, and won a 2008 Young Artist Award for his performance as a sociopathic child following his father's murderous example on the television series Criminal Minds (2005).

He was seen in The Curious Case of Benjamin Button (2008), playing the title character at the age of eight, who has the dementia of an old man.

Additional roles include appearances in Timothy Linh Bui's Powder Blue (2009) and in Universal's Repo Men (2010).

In 2013, he co-starred in The Host and played the lead character opposite Annalise Basso in Standing Up.