The Chapel of the Annunciation is a Medieval Roman Catholic church located in Ħal-Millieri, limits of Żurrieq, Malta.

The now uninhabited village of Ħal-Millieri was first documented in 1419 though it originates from Roman or even pre-historic times.

Its architecture supports this view; the apse was probably a qibla and the building points more or less to Mecca.

[2] Studies on the skeletal remains, of those buried in the medieval period, revealed evidence of the probable first cases of syphilis in Malta.

During Monsignor Pietro Dusina's apostolic visit to Ħal-Millieri, in 1575, he found that there were a total of four churches in the area.

During his visit, Dusina found that the church was in a state of good repair, had three altars and paved.

[6] Maintenance of these frescoes is ongoing and over the years has involved institutions such as Courtaulds, Opificio delle Pietre Dure, the Malta University, Museums Department, and the Restoration Centre.

[7] Archaeologists from the University of Malta and of Oxford discovered a number of medieval coins and pieces of pottery.

In the church yard one can see a number of items dating back to Roman times such as the stone olive mortar.