Charles Azzopardi (21 December 1930 – 28 October 1970) was a Maltese footballer.
A centre-forward or right winger, Azzopardi was part of the famous Floriana side of the 1950s, winning three league titles, two FA Trophy medals and a Cassar Cup with them.
He then had a two-year spell at Rabat FC before returning to Floriana where he retired at only 26 years of age.
Azzopardi was part of the Maltese FA U-20 team at the Palermo Youth Tournament in 1949–50.
His father George Azzopardi also played for Floriana as well as his uncles Manwel and Tony.