He enrolled at Dartmouth College in Rhode Island, but then shortly thereafter he transferred to Brown University where he studied a classical course load of Greek, Latin, logic mathematics, and moral philosophy; however, Jewett showed the greatest interest in languages.
Jewett had a tremendous love for books but he was lacking personal fortune so this made him an avid library user.
Jewett left the Smithsonian after being relieved of his position due to conflicts with his supervisor and the Board of Regents over how the Institution's funds were being allocated.
This catalog would give scholars access to important books, point out differences in intellectual fields, and generally act as an aid to the evolution of knowledge while making the Smithsonian Institution the pre-eminent center for research.
Jewett was hugely concerned with uniformity, and believed stringent rules the only way to avoid confusion, no matter how difficult it made things for users.
Charles Jewett died after suffering an attack of apoplexy while working at his desk in the Boston Public Library.