The Charles Denby Garrison Sr. House is a historic residence near Prichard, Alabama, United States.

The 1+1⁄2-story house was designed by architect Kenneth R. Giddens for a local lumberman, Charles Denby Garrison Sr.

The architectural landscape in the United States following World War II came to be dominated by modern styles, such as the Ranch-style.

Due to its interwar period architectural significance, the house was added to the National Register of Historic Places on September 9, 2009.

This article about a property in Alabama on the National Register of Historic Places is a stub.