Charles F. McMillan (October 25, 1954 – September 6, 2024) was an American nuclear physicist and served as the 10th director of the Los Alamos National Laboratory.

[2] Charles F. McMillan had been Principal Associate Director for Weapons Programs at Los Alamos and joined the laboratory in 2006, where he was responsible for directing the science, technology, engineering, and infrastructure that enables the Laboratory to deliver on its core mission of ensuring the safety, reliability, and performance of the nation's nuclear deterrent.

[4] Prior to joining Los Alamos, McMillan, an experimental physicist, spent more than 20 years at Lawrence Livermore National Laboratory in California, beginning in 1983.

[8] McMillan died in Los Alamos, New Mexico, on September 6, 2024, at the age of 69, as a result of injuries sustained in a traffic collision.

[10] He stressed the importance of Los Alamos to national security, and reflected on the last Divider nuclear test, on September 23, 1992, in Operation Julin.