Charles Frederick Millspaugh (June 20, 1854 – September 15, 1923) was an American botanist and physician, born at Ithaca, New York, and educated at Cornell and the New York Homeopathic Medical College.

He received his medical degree in 1881 and practiced medicine in Binghamton, New York until 1890.

[1] In 1894 he was appointed as the newly established Field Museum of Natural History's first Curator of Botany, a position he held until his death.

Millspaugh conducted explorations in the United States and Mexico, the West Indies, Brazil, and other parts of South America, and was the author of American Medical Plants (1887); Flora of West Virginia (1896); Contribution I-III to the Coastal and Plain Flora of Yucatan (1895-1898); "Flora of Santa Carolina Island" (1923); and many articles in scientific and popular journals.

[3] Books by and about Charles Frederick Millspaugh on WorldCat[4]