Charles H. Spencer House, formerly Christian Science Society and First Church of Christ, Scientist, Grinnell, located in Grinnell, Iowa, in the United States, is an historic Carpenter Gothic house which was converted into a church.

The Charles H. Spencer House was built at the corner of 6th Avenue and Main Street in the late 1860s as a private residence.

Charles H. Spencer was the founder of the First National Bank of Grinnell.

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