[11] The Prince George's County Board of Education considered several names for the school, but ultimately settled on long-time Glenarden resident Charles Herbert Flowers, a well-known trainer of the Tuskegee Airmen.

[14] The building features a gymnasium, a wrestling room, a tennis court, a stadium and an auditorium with 750 seats, and 18 laboratories for science classes.

[16] Today, the uniforms for all students are black khakis with a forest green polo shirt, with any color shoes.

Beginning in the 2011–2012 school year, students in the Science and Technology Program, who have internships during the day, wear an all-black uniform.

Charles Herbert Flowers High School is part of the Prince George's County Science and Technology program.

[17] Previously the school only allowed students already making a 3.0 grade point average and with permission from teachers to sign up for Advanced Placement (AP) courses.

After Jay Mathews of The Washington Post inquired on the matter, principal Helena Nobles-Jones stated that the restriction policy had been dropped.