Charles Holland Mason (August 9, 1822 – June 11, 1894) was a 19th-century American politician and lawyer.
Mason served as United States Commissioner for the Indian Territory (now Oklahoma) from 1890 until his death.
At age twenty-one, he emigrated West, locating first at Louisville, Kentucky where he was employed as tutor in a private family, studying law between school hours with Hamilton Smith.
On March 20, 1852, in Cannelton, Indiana, Mason married Rachel Littell (Huckeby) Wright (1828–1883), the young widow of John G. Wright, the daughter of Joshua B. Huckeby and Rebecca Lang.
In 1890, Mason was appointed by president Benjamin Harrison as United States Commissioner for the Indian Territory (before the organization of Oklahoma) with headquarters at Vinita, where he died in June 1894.