Alongside childhood friend Pharrell Williams, he formed the production duo the Neptunes in 1992,[1] with whom he has produced numerous hit records for various artists.

They formed The Neptunes, and in 1992, upon entering a local talent contest, they were discovered by Teddy Riley, whose studio was close to their school.

After the breakup of NSYNC, they continued to work with group member Justin Timberlake, writing and producing most of his debut solo album, Justified.

[14] Continuing his work with Kenna, Hugo co-produced all tracks on his next three projects: The Black Goodbye EP (2007), Make Sure They See My Face (2007), and Land 2 Air Chronicles II: Imitation Is Suicide Chapter 1 (2013).

Hugo's notable solo production work includes collaborations with Ashlee Simpson, JoJo, E-40, The Internet, and BROCKHAMPTON.

Hugo worked with Baltimore producer and DJ Daniel Biltmore under the name "MSSL CMMND", releasing mixtapes, original productions, and remixes of artists including Rhye, Iamsu!.