Charles Msakila (November 10, 1919 - February 23, 1994) was a Roman Catholic bishop from Tanzania.
He was ordained a priest on August 31, 1947, and was appointed bishop of the Diocese of Karema on November 13, 1958.
The principal consecrator was Pope John XXIII, assisted by Girolamo Bartolomeo Bortignon and Gioacchino Muccin.
Msakila attended the Second Vatican Council and led his diocese until his death.
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