Charles R. Greco (October 15, 1873 – February 22, 1963) was an American architect who worked in the Boston area during the first half of the 20th century.

Upon graduation he worked with the architectural firms of Wait & Cutter from 1893 to 1899, and Peabody & Stearns from 1900 to 1907, before starting his own practice.

Greco designed numerous religious buildings for both Roman Catholic and Jewish congregations in Massachusetts, Florida, and Ohio.

He also provided the designs for many buildings for the city of Cambridge, Massachusetts, including several fire stations.

[1] Greco died February 22, 1963, in Trumbull, Connecticut.