At the turn of the 20th century, eldest son Fred was the first to move to Detroit where an uncle, Albert Fisher, had established Standard Wagon Works during the latter part of the 1880s.
Highly successful, the Fishers expanded their operation into Canada, setting up a plant in Walkerville, Ontario and by 1914 their company had grown to become the world's largest manufacturer of auto bodies.
In 1919, the Fisher brothers sold sixty percent of their company to General Motors Corporation (GM).
In 1928 he purchased the famous Dixiana Farm near Lexington, Kentucky which remained in his family for approximately 60 years.
Son Charles Jr. became president of the National Bank of Detroit and a director of the Reconstruction Finance Corporation during World War II.