Furbush appeared in 12 games between the GCL Tigers and West Michigan Whitecaps in 2007, making 10 starts and going 6–1 with a 2.34 ERA, striking out 69 batters in 61+2⁄3 innings.

[4] On May 21, 2011, Furbush was called up for the first time to replace Brad Thomas who went on the 15-day disabled list with left elbow inflammation.

[5] He made his Major League debut on May 23, 2011, after coming into relief for starter Phil Coke who appeared to hurt his ankle slipping on the wet grass after a short start of only 3+1⁄3 innings pitched and a 1–0 Tigers deficit against the Tampa Bay Rays.

[6] On July 30, 2011, Furbush was traded to the Seattle Mariners along with outfielder Casper Wells, prospect Francisco Martínez and player to be named later Chance Ruffin from the Detroit Tigers for David Pauley and Doug Fister.

On August 10, 2016, Furbush announced that he would have surgery to fix a partially torn rotator cuff, with an expected recovery time of 12–18 months.

In January 2022, it was reported that he was selling advertising time for Seattle radio station ESPN 710 and was said by one 710 staffer to be "a great dude"[12] Furbush throws a steady mix of five pitches.