He made his professional debut in 2011, splitting time between the Double–A Erie SeaWolves and Triple–A Toledo Mud Hens.

[1] On July 25, 2011, Ruffin was selected to the 40-man roster and promoted to the major leagues for the first time.

On August 17, 2011, Ruffin was sent to the Seattle Mariners to complete an earlier trade for Doug Fister and David Pauley.

[4] In 2013, Ruffin made 31 appearances (18 starts) split between Tacoma and the Double–A Jackson Generals, accumulating a 5–6 record and 3.91 ERA with 82 strikeouts across 112+2⁄3 innings.

This biographical article relating to an American baseball pitcher born in the 1980s is a stub.