Charles Knepper (February 18, 1871 – February 6, 1946) was an American professional baseball player who played as a pitcher in Major League Baseball.

Knepper spent just one season in the majors, pitching for the 1899 Cleveland Spiders, a notoriously futile team that set a major league record by losing 134 games.

He also ranked among the National League's leaders in several undesirable pitching categories, including home runs allowed (second, with 11), losses (fourth, with 22), earned runs allowed (seventh, with 141), and wild pitches (tenth, with eight).

During a game on June 24, 1899, he hit a double, and the next day The Plain Dealer's game recap stated that "a hay wagon drawn by lame horses could have reached third, but Knepper is no hay wagon and had no lame horses to assist him".

This biographical article relating to an American baseball pitcher born in the 1870s is a stub.