Developed by Backbone Entertainment, it was released by Sega for Game Boy Advance, Nintendo DS, and Microsoft Windows.

Both titles feature the voice of Dominic Scott Kay, the actor playing Wilbur in the motion picture.

[5][6] In 2007, a separate version of the game was released exclusively in Europe for the PlayStation 2, titled simply Charlotte's Web, excluding the subtitle of Wilbur and Friends.

These sections often involve running around the farm collecting items for other characters while avoiding dogs and farmers that will send the player back to the start of the level.

In addition to this, Charlotte the Spider and Templeton the Rat are also playable in the form of more linear minigames in between Wilbur's levels.