Charlotte Elizabeth Cavendish, Marchioness of Hartington, 6th Baroness Clifford (born Lady Charlotte Boyle; 27 October 1731 – 8 December 1754) was the daughter of Richard Boyle, 3rd Earl of Burlington and Lady Dorothy Savile.

From 1748 until her death, she was married to William Cavendish, Marquess of Hartington, later the 4th Duke of Devonshire and Prime Minister of Great Britain.

Her mother was the daughter of William Savile, 2nd Marquess of Halifax and Lady Mary Finch, daughter of the 2nd Earl of Nottingham[1] On 28 March 1748, she married William Cavendish, then the Marquess of Hartington, who later became the 4th Duke of Devonshire and the Prime Minister of Great Britain.

[1] As the heir of her father, she succeeded to the title of Baroness Clifford of Londesborough suo jure.

[citation needed] These estates included: Burlington House, Piccadilly, London (now the Royal Academy of Arts); Chiswick House, London;[1] Londesborough Hall, Yorkshire; Bolton Abbey, Yorkshire; Lismore Castle, County Waterford, Ireland.