"[5] She was president of the nonsectarian Home for Incurables in Washington, D.C. for over forty years,[6][7] and served on the board of the United States Hospital for the Insane.

[8] She led fundraising for the Ellen Wilson Memorial Homes, a planned housing renewal project in Washington.

During World War I, Hopkins was chair of the Woman's Department of the National Civic Federation, District of Columbia Section, and worked on coordinating women's war relief efforts,[13] for example collecting donations of linen for surgical use,[14] or providing family assistance for the dependents of military personnel.

[15] In March 1933, in her eighties, she gave new First Lady Eleanor Roosevelt a tour of Washington's neighborhoods, and is credited with helping to create the Alley Dwelling Authority in 1934, to improve sanitation and housing in the city.

The Library of Congress has the Charlotte Everett Hopkins Collection of National Civic Federation, Woman's Department, District of Columbia Section Records.