Dr. Charlotte Johnson Baker (March 30, 1855 – October 31, 1937) was an American physician who was the first woman to practice medicine in San Diego, California.

[1] She practiced obstetrics and gynecology at St. Joseph's Hospital, where her husband, Fred Baker, MD, was a general practitioner.

She graduated from Newburyport High School in 1872, and spent a year teaching before enrolling in Vassar College in 1873.

In January 1888, the family moved to San Diego, California, where Baker and her husband became successful physicians, settling in Roseville in the Point Loma area.

Also in 1888, Baker earned a Master of Arts from Vassar College for her special work in optics and ophthalmology done after graduation.