[4] Her first marriage was when she was aged 15, to Damasio Alipás (or Alipaz), and had three children, Romana, Maria Arcadia who married Point Loma lighthouse keeper Captain Robert D. Israel and Josefa.
[4] As young adults, José was sent back to be brought up in Boston, but offended at his uncle having a black servant, ran away to sea, and became a whaler and married in Chile.
She fostered orphaned or sick children, including a son of an American couple, Diego Hunter, whose mother had died in childbirth and father, a soldier, had to return to America.
However later in life, her lack of documentation meant that she effectively lost her assets in the changes of governments, and so died in relative poverty, whilst living with her daughter Maria Arcadia Israel.
[4] An exhibition was created recognising Wrightington's contribution to the Old Town of San Diego through the Spanish, Mexican and American era, and also noting her personal dedication to the native people she served as a nurse and translator.