Alexandra required her services more when she was in mourning, for example when her son, Prince Albert Victor, Duke of Clarence and Avondale, died in 1892.

Upon Edward's ascension to the throne, when Queen Victoria died in 1901, Charlotte was officially installed at Alexandra's side as a Woman of the Bedchamber.

[4] The new king Edward VII granted her the style the Honourable and precedence as the daughter of a baron, after her brother became Viscount Knollys.

Charlotte wrote in a letter dated a year before Alexandra's death in 1925:H.M. is so fond of Sandringham...she readily falls in with the doctor's advice that she should not tire herself with all the hurry and bustle of the Season...As far as I'm concerned, I am a "Cockney born and bred", and down here I can never see my friends and relations and seem quite cut off from all the world.Her leave of service came upon Alexandra's death in 1925.

During her service, she was credited as the first woman private secretary to the Sovereign, and the first person not of royal blood to enter the Queen's boudoir without invitation.