Charlotte Osborne, Duchess of Leeds (16 March 1776 – 30 July 1856), formerly Lady Charlotte Townshend, was the wife of George Osborne, 6th Duke of Leeds.

[1] She was the daughter of George Townshend, 1st Marquess Townshend, by his second wife, the former Anne Montgomery.

On 17 August 1797, Osborne married the duke, then Marquess of Carmarthen, at East Raynham in Norfolk[2] In 1799 Osborne's husband became duke, and therefore, she became a duchess.

They had three children: The Duke of Leeds died in 1838, aged 62, to be succeeded by their son, Francis.

The Duchess of Leeds died in July 1856, aged 80.